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Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression

Subjecting cardiomyocytes to mechanical stress or neurohumoral stimulation causes cardiac hypertrophy characterized in part by reactivation of the fetal cardiac gene program. Here we demonstrate a new common mechanism by which these stimuli are transduced to a signal activating the hypertrophic gene...

詳細記述

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書誌詳細
主要な著者: Kuwahara, Koichiro, Kinoshita, Hideyuki, Kuwabara, Yoshihiro, Nakagawa, Yasuaki, Usami, Satoru, Minami, Takeya, Yamada, Yuko, Fujiwara, Masataka, Nakao, Kazuwa
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937559/
https://ncbi.nlm.nih.gov/pubmed/20606005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00154-10
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