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The Molecular Basis of Phospholipase D2-Induced Chemotaxis: Elucidation of Differential Pathways in Macrophages and Fibroblasts

We report the molecular mechanisms that underlie chemotaxis of macrophages and cell migration of fibroblasts, cells that are essential during the body's innate immune response and during wound repair, respectively. Silencing of phospholipase D1 (PLD1) and PLD2 reduced cell migration (both chemo...

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Библиографические подробности
Главные авторы: Knapek, Katie, Frondorf, Kathleen, Post, Jennalee, Short, Stephen, Cox, Dianne, Gomez-Cambronero, Julian
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937534/
https://ncbi.nlm.nih.gov/pubmed/20647543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00229-10
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