Immunization with a Combination of Integral Chlamydial Antigens and a Defined Secreted Protein Induces Robust Immunity against Genital Chlamydial Challenge

We have previously demonstrated the efficacy of recombinant chlamydial protease-like activity factor (rCPAF; a secreted chlamydial protein) in inducing antigen-specific CD4(+) T cell/gamma interferon (IFN-γ)-mediated but not antibody-mediated chlamydial clearance and reduction of upper genital tract...

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Hlavní autoři: Li, Weidang, Murthy, Ashlesh K., Guentzel, M. Neal, Chambers, James P., Forsthuber, Thomas G., Seshu, J., Zhong, Guangming, Arulanandam, Bernard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937460/
https://ncbi.nlm.nih.gov/pubmed/20605976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00346-10
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