Heat Denatured Enzymatically Inactive Recombinant Chlamydial Protease-Like Activity Factor Induces Robust Protective Immunity Against Genital Chlamydial Challenge

We have shown previously that vaccination with recombinant chlamydial protease-like activity factor (rCPAF) plus interleukin-12 as an adjuvant induces robust protective immunity against primary genital Chlamydia muridarum challenge in mice. Since CPAF is a protease, we compared the effects of enzyma...

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Detalhes bibliográficos
Main Authors: Chaganty, Bharat K. R., Murthy, Ashlesh K., Evani, Shankar J., Li, Weidang, Guentzel, M. Neal, Chambers, James P., Zhong, Guangming, Arulanandam, Bernard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846592/
https://ncbi.nlm.nih.gov/pubmed/20056182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.12.064
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