Chlamydial Protease-Like Activity Factor Induces Protective Immunity against Genital Chlamydial Infection in Transgenic Mice That Express the Human HLA-DR4 Allele

There is no licensed vaccine available against Chlamydia trachomatis, the leading cause of bacterial sexually transmitted disease. We have found that intranasal immunization with recombinant chlamydial protease-like activity factor (CPAF) induces CD4(+) T-cell- and gamma interferon (IFN-γ)-dependent...

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Hlavní autoři: Murthy, Ashlesh K., Cong, Yu, Murphey, Cathi, Guentzel, M. Neal, Forsthuber, Thomas G., Zhong, Guangming, Arulanandam, Bernard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Bacterial Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698050/
https://ncbi.nlm.nih.gov/pubmed/17015458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01119-06
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