Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms

Neutrophils rely on exocytosis to mobilize receptors and adhesion molecules and to release microbicidal factors. This process should be strictly regulated because uncontrolled release of toxic proteins would be injurious to the host. In vivo studies showed that the small GTPase Rab27a regulates azur...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Johnson, Jennifer L., Brzezinska, Agnieszka A., Tolmachova, Tanya, Munafo, Daniela B., Ellis, Beverly A., Seabra, Miguel C, Hong, Hong, Catz, Sergio D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937183/
https://ncbi.nlm.nih.gov/pubmed/20028487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2009.01029.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi