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Sodium channel SCN1A and epilepsy: mutations and mechanisms

Mutations in a number of genes encoding voltage-gated sodium channels cause a variety of epilepsy syndromes in humans, including genetic (generalized) epilepsy with febrile seizures Plus (GEFS+) and Dravet syndrome (DS, severe myoclonic epilepsy of infancy). The vast majority of these mutations are...

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Main Authors: Escayg, Andrew, Goldin, Alan L.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937162/
https://ncbi.nlm.nih.gov/pubmed/20831750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02640.x
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