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E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila
The ability of ionizing radiation (IR) to induce apoptosis independently of p53 is crucial for successful therapy of cancers bearing p53 mutations. p53-independent apoptosis, however, remains poorly understood relative to p53-dependent apoptosis. IR induces both p53-dependent and p53-independent apo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937093/ https://ncbi.nlm.nih.gov/pubmed/20659447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.023 |
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