E2F and p53 Induce Apoptosis Independently during Drosophila Development but Intersect in the Context of DNA Damage

In mammalian cells, RB/E2F and p53 are intimately connected, and crosstalk between these pathways is critical for the induction of cell cycle arrest or cell death in response to cellular stresses. Here we have investigated the genetic interactions between RBF/E2F and p53 pathways during Drosophila d...

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Main Authors: Moon, Nam-Sung, Di Stefano, Luisa, Morris, Erick J., Patel, Reena, White, Kristin, Dyson, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491587/
https://ncbi.nlm.nih.gov/pubmed/18688282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000153
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