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E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila

The ability of ionizing radiation (IR) to induce apoptosis independently of p53 is crucial for successful therapy of cancers bearing p53 mutations. p53-independent apoptosis, however, remains poorly understood relative to p53-dependent apoptosis. IR induces both p53-dependent and p53-independent apo...

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Detalhes bibliográficos
Main Authors: Wichmann, Anita, Uyetake, Lyle, Su, Tin Tin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937093/
https://ncbi.nlm.nih.gov/pubmed/20659447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.023
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