Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2−/− mice

Anterior Gradient 2 (AGR2) is a protein disulfide isomerase that plays important roles in diverse processes in multiple cell lineages as a developmental regulator, survival factor and susceptibility gene for inflammatory bowel disease. Here, we show using germline and inducible Agr2−/− mice that Agr...

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Hlavní autoři: Zhao, Fang, Edwards, Robert, Dizon, Diana, Mastroianni, Jennifer R., Geyfman, Mikhail, Ouellette, André J., Andersen, Bogi, Lipkin, Steven M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937056/
https://ncbi.nlm.nih.gov/pubmed/20025862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.12.008
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