Flavonoids exert distinct modulatory actions on cyclooxygenase 2 and NF-κB in an intestinal epithelial cell line (IEC18)

BACKGROUND AND PURPOSE: Cyclooxygenase 2 (COX-2) is involved in inflammatory bowel disease, but the effect of flavonoids at the intestinal epithelial level is unknown. We aimed to characterize the effect and structure-activity relationship of nine selected flavonoids on COX-2 expression in intestina...

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Detalhes bibliográficos
Main Authors: López-Posadas, R, Ballester, I, Mascaraque, C, Suárez, MD, Zarzuelo, A, Martínez-Augustin, O, Sánchez de Medina, F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936843/
https://ncbi.nlm.nih.gov/pubmed/20649574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00827.x
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