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Identification of a Strigoterpenoid with Dual Nrf2 and Nf-κB Modulatory Activity
[Image: see text] The sesquiterpene–coumarin ether samarcandone provided a suitable framework to replace the apocarotenoid A–C ring system of strigol (1), replicating, after linking to a butenolide moiety, the activity of the natural phytohormone on Nrf2 and also showing potent NF-kB inhibitory acti...
Guardat en:
| Publicat a: | ACS Med Chem Lett |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2019
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467025/ https://ncbi.nlm.nih.gov/pubmed/30996804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00604 |
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