The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats

BACKGROUND AND PURPOSE: The nitrogen-containing bisphosphonates are drugs used successfully in the treatment of osteoporosis. They act inhibiting farnesyl diphosphate synthase. This mechanism may also produce anti-inflammatory effects. The therapeutic activity of alendronate was tested in vivo using...

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Detalhes bibliográficos
Main Authors: Ballester, I, Daddaoua, A, López-Posadas, R, Nieto, A, Suárez, M D, Zarzuelo, A, Martínez-Augustin, O, de Medina, F Sánchez
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013953/
https://ncbi.nlm.nih.gov/pubmed/17375077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707227
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