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Suppression of Liver Regeneration and Hepatocyte Proliferation in Glypican 3 Hepatocyte-targeted Transgenic Mice
Glypican 3 (GPC3) belongs to a family of glycosylphosphatidylinositol-anchored, cell-surface heparan sulfate proteoglycans. GPC3 is over-expressed in hepatocellular carcinomas (HCC). Loss-of-function mutations of GPC3 result in the Simpson-Golabi-Behmel syndrome, an X-linked disorder characterized b...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936713/ https://ncbi.nlm.nih.gov/pubmed/20812357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23794 |
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