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An inexpensive, specific and highly sensitive protocol to detect the Braf(V600E) mutation in melanoma tumor biopsies and blood

The Braf(V600E) mutation has been detected in patients with metastatic melanoma, colon, thyroid and other cancer. Recent studies suggested that tumors with this mutation are especially sensitive to Braf inhibitors-hence the need to reliably determine the Braf status of tumor specimens. The present t...

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Detalhes bibliográficos
Main Authors: Panka, David J, Sullivan, Ryan J, Mier, James W
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936688/
https://ncbi.nlm.nih.gov/pubmed/20679909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0b013e32833d8d48
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