Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

The rapid induction of type I IFN is a central event of the innate defense against viral infections and is tightly regulated by a number of cellular molecules. Viral components induce strong type I IFN responses through the activation of toll-like receptors (TLRs) and intracellular cytoplasmic recep...

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Библиографические подробности
Главные авторы: Arimoto, Kei-ichiro, Funami, Kenji, Saeki, Yasushi, Tanaka, Keiji, Okawa, Katsuya, Takeuchi, Osamu, Akira, Shizuo, Murakami, Yoshiki, Shimotohno, Kunitada
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936632/
https://ncbi.nlm.nih.gov/pubmed/20724660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004621107
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