Extracellular DNA traps promote thrombosis

Neutrophil extracellular traps (NETs) are part of the innate immune response to infections. NETs are a meshwork of DNA fibers comprising histones and antimicrobial proteins. Microbes are immobilized in NETs and encounter a locally high and lethal concentration of effector proteins. Recent studies sh...

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Bibliografiske detaljer
Main Authors: Fuchs, Tobias A., Brill, Alexander, Duerschmied, Daniel, Schatzberg, Daphne, Monestier, Marc, Myers, Daniel D., Wrobleski, Shirley K., Wakefield, Thomas W., Hartwig, John H., Wagner, Denisa D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936604/
https://ncbi.nlm.nih.gov/pubmed/20798043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005743107
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