Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury

BACKGROUND: Cystic fibrosis is a debilitating lung disease due to mutations in the cystic fibrosis transmembrane conductance regulator protein (CFTR) and is associated with chronic infections resulting in elevated myeloperoxidase activity and generation of hypochlorous acid (HOCl). CFTR mutations le...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gould, Neal S, Gauthier, Steve, Kariya, Chirag T, Min, Elysia, Huang, Jie, Brian, Day J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936384/
https://ncbi.nlm.nih.gov/pubmed/20799947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-119
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