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Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity

BACKGROUND: Constraint-based models enable structured cellular representations in which intracellular kinetics are circumvented. These models, combined with experimental data, are useful analytical tools to estimate the state exhibited (the phenotype) by the cells at given pseudo-steady conditions....

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Autors principals: Tortajada, Marta, Llaneras, Francisco, Picó, Jesús
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936294/
https://ncbi.nlm.nih.gov/pubmed/20716335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-115
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