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Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity

BACKGROUND: Constraint-based models enable structured cellular representations in which intracellular kinetics are circumvented. These models, combined with experimental data, are useful analytical tools to estimate the state exhibited (the phenotype) by the cells at given pseudo-steady conditions....

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Detalhes bibliográficos
Main Authors: Tortajada, Marta, Llaneras, Francisco, Picó, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936294/
https://ncbi.nlm.nih.gov/pubmed/20716335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-115
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