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Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity

BACKGROUND: Constraint-based models enable structured cellular representations in which intracellular kinetics are circumvented. These models, combined with experimental data, are useful analytical tools to estimate the state exhibited (the phenotype) by the cells at given pseudo-steady conditions....

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Main Authors: Tortajada, Marta, Llaneras, Francisco, Picó, Jesús
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936294/
https://ncbi.nlm.nih.gov/pubmed/20716335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-115
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