In vitro modulation of cisplatin accumulation in human ovarian carcinoma cells by pharmacologic alteration of microtubules.

We have previously shown that forskolin and 3-isobutyl-1-methylxanthine (IBMX) increased accumulation of cisplatin (DDP) in DDP-sensitive 2008 human ovarian carcinoma cells in proportion to their ability to increase cAMP. Since the major function of cAMP is to activate protein kinase A, it was conje...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Christen, R D, Jekunen, A P, Jones, J A, Thiebaut, F, Shalinsky, D R, Howell, S B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1993
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC293629/
https://ncbi.nlm.nih.gov/pubmed/8100837
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