Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin.

Cisplatin (DDP) is the most effective drug for the treatment of human ovarian cancer, but the mechanisms that determine sensitivity to the cytotoxic action of DDP are not well understood. Treatment of two human ovarian carcinoma cell lines with epidermal growth factor (EGF) simultaneously increased...

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Detalhes bibliográficos
Main Authors: Christen, R D, Hom, D K, Porter, D C, Andrews, P A, MacLeod, C L, Hafstrom, L, Howell, S B
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296913/
https://ncbi.nlm.nih.gov/pubmed/2243136
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