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Tamoxifen delays the development of resistance to cisplatin in human melanoma and ovarian cancer cell lines.

The development of resistance to cisplatin (DDP) occurs rapidly both in vitro and in vivo, and constitutes a major obstacle to effective therapy. We have previously demonstrated that there is a highly synergistic interaction between tamoxifen (TAM) and DDP against cell lines representative of three...

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Bibliographic Details
Main Authors: McClay, E. F., Albright, K. D., Jones, J. A., Christen, R. D., Howell, S. B.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033375/
https://ncbi.nlm.nih.gov/pubmed/8080729
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