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Tamoxifen delays the development of resistance to cisplatin in human melanoma and ovarian cancer cell lines.

The development of resistance to cisplatin (DDP) occurs rapidly both in vitro and in vivo, and constitutes a major obstacle to effective therapy. We have previously demonstrated that there is a highly synergistic interaction between tamoxifen (TAM) and DDP against cell lines representative of three...

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Autori principali: McClay, E. F., Albright, K. D., Jones, J. A., Christen, R. D., Howell, S. B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033375/
https://ncbi.nlm.nih.gov/pubmed/8080729
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