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CDK8 Is a Stimulus-Specific Positive Coregulator of p53 Target Genes
The p53 transcriptional network orchestrates alternative stress responses such as cell-cycle arrest and apoptosis. Here we investigate the mechanism of differential expression of p21, a key mediator of p53-dependent cell-cycle arrest. We demonstrate that the transcriptional activity of the p21 promo...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936241/ https://ncbi.nlm.nih.gov/pubmed/17612495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.05.026 |
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