Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes.

To elucidate the cellular mechanism by which angiotensin II (ANG II) induces cardiac hypertrophy, we investigated the possible autocrine/paracrine role of endogenous endothelin-1 (ET-1) in ANG II-induced hypertrophy of neonatal rat cardiomyocytes by use of synthetic ET-1 receptor antagonist and anti...

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Detalhes bibliográficos
Main Authors: Ito, H, Hirata, Y, Adachi, S, Tanaka, M, Tsujino, M, Koike, A, Nogami, A, Murumo, F, Hiroe, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC293624/
https://ncbi.nlm.nih.gov/pubmed/8326007
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