Pharmacological pre- and post-conditioning with the sphingosine-1-phosphate receptor modulator FTY720 after myocardial ischaemia–reperfusion

BACKGROUND AND PURPOSE: Our recent experiments demonstrated that the Sphingosine-1-phosphate (S1P) receptor agonist FTY720 (2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride) improves recovery of function after myocardial ischaemia–reperfusion ex vivo. Therefore, we tested the hypothe...

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Detalhes bibliográficos
Main Authors: Hofmann, U, Hu, K, Walter, F, Burkard, N, Ertl, G, Bauersachs, J, Ritter, O, Frantz, S, Bonz, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936032/
https://ncbi.nlm.nih.gov/pubmed/20590616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00767.x
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