Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

BACKGROUND AND PURPOSE: Pancreatic cancer is a highly aggressive malignancy, and improvement in systemic therapy is necessary to treat this frequently encountered metastatic disease. The current targeted agents used in combination with gemcitabine improved objective response rates, but with little o...

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Autors principals: Iwanski, Gabriela B, Lee, Dhong H, En-Gal, Shlomit, Doan, Ngan B, Castor, Brandon, Vogt, Marco, Toh, Melvin, Bokemeyer, Carsten, Said, Jonathan W, Thoennissen, Nils H, Koeffler, H Phillip
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936004/
https://ncbi.nlm.nih.gov/pubmed/20590594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00741.x
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