RNA interference, growth and differentiation appear normal in African trypanosomes lacking Tudor staphylococcal nuclease

Ribonucleases play important roles in the RNA interference (RNAi) pathway. The Dicer endonuclease converts double-stranded (ds)RNA into small interfering (si)RNA and the Slicer endonuclease, as a component of the RNA induced silencing complex (RISC), cleaves mRNA. Tudor staphylococcal nuclease (Tudo...

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Autori principali: Alsford, Sam, Kemp, Louise E., Kawahara, Taemi, Horn, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier/North-Holland Biomedical Press 2010
Soggetti:
Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935966/
https://ncbi.nlm.nih.gov/pubmed/20558212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.06.006
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