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Elongator Protein 3b Negatively Regulates Ribosomal DNA Transcription in African Trypanosomes

Eukaryotic cells limit ribosomal DNA (rDNA) transcription by RNA polymerase I (RNAP-I) to maintain genome integrity. African trypanosomes present an excellent model for studies on RNAP-I regulation because they possess a bifunctional RNAP-I and because RNAP-II transcription appears unregulated. Sinc...

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Detalhes bibliográficos
Main Authors: Alsford, Sam, Horn, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133226/
https://ncbi.nlm.nih.gov/pubmed/21357738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01026-10
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