A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions

Autophagy is a cellular catabolic mechanism that plays an essential function in protecting multicellular eukaryotes from neurodegeneration, cancer and other diseases. However, we still know very little about mechanisms regulating autophagy under normal homeostatic conditions when nutrients are not l...

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Bibliografiset tiedot
Päätekijät: Lipinski, Marta M., Hoffman, Greg, Ng, Aylwin, Zhou, Wen, Py, Bénédicte F., Hsu, Emily, Liu, Xuxin, Eisenberg, Jason, Liu, Jun, Blenis, John, Xavier, Ramnik J., Yuan, Junying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935848/
https://ncbi.nlm.nih.gov/pubmed/20627085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.005
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