A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions

Autophagy is a cellular catabolic mechanism that plays an essential function in protecting multicellular eukaryotes from neurodegeneration, cancer and other diseases. However, we still know very little about mechanisms regulating autophagy under normal homeostatic conditions when nutrients are not l...

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Detalhes bibliográficos
Main Authors: Lipinski, Marta M., Hoffman, Greg, Ng, Aylwin, Zhou, Wen, Py, Bénédicte F., Hsu, Emily, Liu, Xuxin, Eisenberg, Jason, Liu, Jun, Blenis, John, Xavier, Ramnik J., Yuan, Junying
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935848/
https://ncbi.nlm.nih.gov/pubmed/20627085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.005
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