Dual Inhibitor AEE788 Reduces Tumor Growth in Preclinical Models of Medulloblastoma

Medulloblastoma is the most frequent malignant pediatric brain tumor with a dismal prognosis in 30% of cases. We examined the activity of AEE788, a dual inhibitor of human epidermal receptor (HER) 1/2 and vascular endothelial growth factor receptor (VEGFR) 1/2, in medulloblastoma preclinical models....

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Autors principals: Meco, Daniela, Servidei, Tiziana, Zannoni, Gian Franco, Martinelli, Enrica, Prisco, Maria Grazia, de Waure, Chiara, Riccardi, Riccardo
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935636/
https://ncbi.nlm.nih.gov/pubmed/20885895
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