Gender Effect in Experimental Models of Human Medulloblastoma: Does the Estrogen Receptor β Signaling Play a Role?

BACKGROUND: The male-to-female sex ratio for medulloblastoma (MB) is approximately 1.5∶1, female gender being also a favorable prognostic factor. This study aimed at evaluating the impact of gender on MB tumorigenesis. METHODS: In vitro activity of 17β-estradiol (E(2)), DPN [2,3-bis(4-hydroxyphenyl)...

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Detalhes bibliográficos
Main Authors: Ciucci, Alessandra, Meco, Daniela, De Stefano, Ilaria, Travaglia, Daniele, Zannoni, Gian Franco, Scambia, Giovanni, Riccardi, Riccardo, Saran, Anna, Mancuso, Mariateresa, Gallo, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084991/
https://ncbi.nlm.nih.gov/pubmed/25000562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101623
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