Antitumor Activity of IMC-038525, a Novel Oral Tubulin Polymerization Inhibitor

Microtubules are a well-validated target for anticancer therapy. Molecules that bind tubulin affect dynamic instability of microtubules causing mitotic arrest of proliferating cells, leading to cell death and tumor growth inhibition. Natural antitubulin agents such as taxanes and Vinca alkaloids hav...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tuma, Maria Carolina, Malikzay, Asra, Ouyang, Xiaohu, Surguladze, David, Fleming, James, Mitelman, Stan, Camara, Margarita, Finnerty, Bridget, Doody, Jacqueline, Chekler, Eugene L P, Kussie, Paul, Tonra, James R
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935635/
https://ncbi.nlm.nih.gov/pubmed/20885894
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados