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Discovery of Dual VEGFR-2 and Tubulin Inhibitors with in Vivo Efficacy
[Image: see text] In an effort to develop potent, orally bioavailable compounds for the treatment of neoplastic diseases, we developed a class of dual VEGFR-2 kinase and tubulin inhibitors. Targeting the VEGFR receptor kinase and tubulin structure allows for inhibition of both tumor cells and tumor...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2010
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007844/ https://ncbi.nlm.nih.gov/pubmed/24900236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1001568 |
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