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Induced Chromosomal Proximity and the Genesis of Gene Fusions in Prostate Cancer
Gene fusions have a critical role in cancer progression. Mechanisms associated with the genesis and cell type specificity of these fusions are not well understood. A prototypical gene fusion, TMPRSS2-ERG, involves the 5’ untranslated region of the androgen-regulated gene TMPRSS2 with the ERG gene, a...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935583/ https://ncbi.nlm.nih.gov/pubmed/19933109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178124 |
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