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Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus
Crystal structures of a binary Mg(2+)-form Dpo4–DNA complex with 1,N (2)-etheno-dG in the template strand as well as of ternary Mg(2+)-form Dpo4–DNA–dCTP/dGTP complexes with 8-oxoG in the template strand have been determined. Comparison of their conformations and active-site geometries with those of...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935216/ https://ncbi.nlm.nih.gov/pubmed/20823515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110029374 |
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