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Evolution of the total syntheses of ustiloxin natural products and their analogues
Ustiloxins A–F are antimitotic heterodetic cyclopeptides containing a 13–membered cyclic core structure with a synthetically challenging chiral tertiary alkyl–aryl ether linkage. The first total synthesis of ustiloxin D was achieved in 31 linear steps using an S(N)Ar reaction. An nOe study of this s...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935141/ https://ncbi.nlm.nih.gov/pubmed/18229928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja710363p |
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