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Structure–activity relationships of ustiloxin analogues
Four novel ustiloxin D analogues were synthesized focusing on the size of the macrocyclic core, the stereochemistry at the bridgehead ether, and the enantiomer of ustiloxin D. All four were subjected to biological evaluation testing the inhibition of tubulin polymerization. Only 2,2-dimethyl-ustilox...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098461/ https://ncbi.nlm.nih.gov/pubmed/21607116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.11.165 |
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