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Simple Genetic Selection Protocol for Isolation of Overexpressed Genes That Enhance Accumulation of Membrane-Integrated Human G Protein-Coupled Receptors in Escherichia coli

The efficient production of membrane proteins in bacteria remains a major challenge. In this work, we sought to identify overexpressed genes that enhance the yields of recombinant membrane proteins in Escherichia coli. We developed a genetic selection system for bacterial membrane protein production...

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Detalhes bibliográficos
Principais autores: Skretas, Georgios, Georgiou, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935035/
https://ncbi.nlm.nih.gov/pubmed/20639362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00963-10
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