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Comprehensive Engineering of Escherichia coli for Enhanced Expression of IgG Antibodies

The expression of IgG antibodies in Escherichia coli is of increasing interest for analytical and therapeutic applications. In this work, we describe a comprehensive and systematic approach to the development of a dicistronic expression system for enhanced IgG expression in E. coli encompassing: (i)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Makino, Tomohiro, Skretas, Georgios, Kang, Tae Hyun, Georgiou, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057344/
https://ncbi.nlm.nih.gov/pubmed/21130896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2010.11.002
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