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Steady-State Intrapulmonary Pharmacokinetics and Pharmacodynamics of Posaconazole in Lung Transplant Recipients

This prospective study evaluated the plasma and intrapulmonary pharmacokinetics and pharmacodynamics (PKPD) of posaconazole (POS) in lung transplant recipients. Twenty adult lung transplant patients were instructed to take a 400-mg POS oral suspension twice daily (BID) with a high-fat meal for a tot...

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Detalhes bibliográficos
Main Authors: Conte, John E., DeVoe, Catherine, Little, Emily, Golden, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934990/
https://ncbi.nlm.nih.gov/pubmed/20516276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01396-09
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