Intrapulmonary Pharmacokinetics and Pharmacodynamics of Itraconazole and 14-Hydroxyitraconazole at Steady State

We determined the steady-state intrapulmonary pharmacokinetic and pharmacodynamic parameters of orally administered itraconazole (ITRA), 200 mg every 12 h (twice a day [b.i.d.]), on an empty stomach, for a total of 10 doses, in 26 healthy volunteers. Five subgroups each underwent standardized bronch...

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Bibliografiset tiedot
Päätekijät: Conte, John E., Golden, Jeffrey A., Kipps, Juliana, McIver, Marina, Zurlinden, Elisabeth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Clinical Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC521869/
https://ncbi.nlm.nih.gov/pubmed/15388441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3823-3827.2004
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