Hydroxymethylnitrofurazone Is Active in a Murine Model of Chagas' Disease

The addition of a hydroxymethyl group to the antimicrobial drug nitrofurazone generated hydroxymethylnitrofurazone (NFOH), which had reduced toxicity when its activity against Trypanosoma cruzi was tested in a murine model of Chagas' disease. Four groups of 12 Swiss female mice each received 15...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Davies, Carolina, Cardozo, Rubén Marino, Negrette, Olga Sánchez, Mora, María Celia, Chung, Man Chin, Basombrío, Miguel Ángel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934987/
https://ncbi.nlm.nih.gov/pubmed/20566772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01451-09
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