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Hydroxymethylnitrofurazone Is Active in a Murine Model of Chagas' Disease
The addition of a hydroxymethyl group to the antimicrobial drug nitrofurazone generated hydroxymethylnitrofurazone (NFOH), which had reduced toxicity when its activity against Trypanosoma cruzi was tested in a murine model of Chagas' disease. Four groups of 12 Swiss female mice each received 15...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934987/ https://ncbi.nlm.nih.gov/pubmed/20566772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01451-09 |
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