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APOE is not associated with Alzheimer Disease: a cautionary tale of genotype imputation
The use of genotype imputation methods are becoming increasingly common. They are of particular use in meta-analyses, where data from different genotyping platforms are imputed to a reference set and combined in a joint analysis. We show here that such a meta-analysis can miss strong genetic associa...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934779/ https://ncbi.nlm.nih.gov/pubmed/20529013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00573.x |
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