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APOE is not associated with Alzheimer Disease: a cautionary tale of genotype imputation

The use of genotype imputation methods are becoming increasingly common. They are of particular use in meta-analyses, where data from different genotyping platforms are imputed to a reference set and combined in a joint analysis. We show here that such a meta-analysis can miss strong genetic associa...

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Detaylı Bibliyografya
Asıl Yazarlar: Beecham, Gary W., Martin, Eden R., Gilbert, John R., Haines, Jonathan L., Pericak-Vance, Margaret A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934779/
https://ncbi.nlm.nih.gov/pubmed/20529013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00573.x
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