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A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency

In rodents, the naïve early epiblast undergoes profound morphogenetic, transcriptional and epigenetic changes after implantation. These differences are maintained between blastocyst-derived embryonic stem (ES) cells and egg cylinder-derived epiblast stem cells (EpiSCs). Notably, ES cells robustly co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Ge, Smith, Austin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934732/
https://ncbi.nlm.nih.gov/pubmed/20823062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.052753
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