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A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency

In rodents, the naïve early epiblast undergoes profound morphogenetic, transcriptional and epigenetic changes after implantation. These differences are maintained between blastocyst-derived embryonic stem (ES) cells and egg cylinder-derived epiblast stem cells (EpiSCs). Notably, ES cells robustly co...

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Detalhes bibliográficos
Main Authors: Guo, Ge, Smith, Austin
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934732/
https://ncbi.nlm.nih.gov/pubmed/20823062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.052753
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